Glaucoma is a chronic neurodegenerative disease characterized by apoptosis of retinal ganglion cells and subsequent loss of visual function. Early detection of glaucoma is critical for the prevention of permanent structural damage and irreversible vision loss.
Raman spectroscopy is a technique that provides rapid biochemical characterization of tissues in a non-destructive and non-invasive fashion. In this study, we explored the potential of using Raman spectroscopy for detection of glaucomatous changes in vitro. Raman spectroscopic imaging was conducted on retinal tissues of healthy dogs and dogs with elevated intraocular pressure, compressive optic neuropath, and glaucoma. The Raman spectra were subjected to multivariate discriminant analysis and a classification model was developed to differentiate disease tissues vs. healthy tissues. It was demonstrated in this study that Raman spectroscopic screening has the potential to become a powerful clinical research tool for the detection and characterization of early stage disease.
Join us for this webinar where will discuss the potential of using Raman spectroscopy for detection of glaucomatous changes in retinal tissues in vitro.
During this webinar we will discuss:
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