Thermo Fisher Scientific

ASMS 2016

San Antonio, TX • June 5 – 9, 2016

You are the driving force behind scientific breakthroughs and discoveries. Join us at the 64th ASMS Conference on Mass Spectrometry and Allied Topics as we continue our mission to translate innovation into results using mass spectrometry. From leading edge biological research to translational medicine, to innovations for the applied markets, come and meet our scientists and representatives to discuss how we can partner with you to solve your toughest analytical challenges.

  • Attend our Users’ Meeting and hear from two renowned keynote speakers as they discuss their latest research. Then join one of four parallel application sessions to learn more about cutting-edge developments in your chosen area of interest.
  • Join us for our annual Customer Appreciation Event at the historic Sunset Station to enjoy the culture, food, and live music of San Antonio!
  • In the evenings, visit our Hospitality Suites and discover our latest mass spectrometry and software solutions. Enjoy food and refreshments while networking with your colleagues and our specialists.
  • Attend our Breakfast Workshops to hear about the latest innovations in mass spectrometry technologies and solutions from Thermo Fisher Scientific experts and fellow scientists.
  • Visit us in booth 319 to see how we are translating innovation into results to solve your challenges.

 

Booth 319

Hours

Sunday, June 57:45 p.m.9:30 p.m.
Monday, June 69:00 a.m.5:00 p.m.
Tuesday, June 79:00 a.m.5:00 p.m.
Wednesday, June 89:00 a.m.5:00 p.m.
Thursday, June 99:00 a.m.2:30 p.m.

Hospitality Suites

Connect with us in our two hospitality suites featuring MS technologies and software solutions.

Monday, June 6 – Wednesday, June 8

Grand Hyatt Hotel
600 E Market Street

Texas Ballroom D (MS Technologies)
Republic A, B, and C (Software Solutions)

Thermo Scientific Annual Users’ Meeting

Sunday, June 5th
7:30 a.m. – 12:15 p.m.

Henry B. Gonzalez Convention Center
Lila Cockrell Theater and Room 6
900 East Market St, San Antonio, TX 78205

Register for our annual User’s Meeting and see how we are translating innovation into results using mass spectrometry. From leading edge biological research to translational medicine, to Orbitrap MS innovations for the applied markets, hear from renowned guest speakers during our plenary sessions, followed by four parallel tracks in proteomics & metabolomics, pharma/biopharma, environmental & food safety, and clinical research/forensics toxicology.

Registration

7:30 – 8:00 a.m.

Plenary Speakers

8:00 – 9:30 a.m.

Getting Ready for Clinical Proteomics

Akhilesh Pandey, M.D., Ph.D.
Johns Hopkins University School of Medicine

Targeted approaches using Orbitrap technology in parallel reaction monitoring (PRM) mode are being increasingly applied for rapid, high-throughput and quantitative measurements of both modified and unmodified peptides in a variety of settings. However, the application of these proteomic technologies to a clinical setting has lagged far behind. I will discuss examples where we have initiated the use of discovery and targeted studies to harness the power of mass spectrometry and apply it in a clinical setting. This includes rapid diagnosis of microbes (Mycobacterium tuberculosis and Klebsiella pneumoniae) as well as markers of antibiotic resistance. I will also discuss how mass spectrometry can be used to identify protein deposits in amyloidosis from formalin fixed paraffin-embedded (FFPE) sections for histologic analysis. Finally, I will discuss how PRM experiments can be used for quantifying biomarkers such as HER2 in a clinical setting.

High-throughput Profiling of HLA Allele-specific Peptides by MS for Improved Epitope Predictions

Jennifer Abelin, Ph.D.
Broad Institute

Adaptive immune responses rely on the ability of cytotoxic T cells to identify and eliminate cells displaying disease-specific antigens on human leukocyte antigen (HLA) molecules. Therefore, investigations into antigen processing and display have immense implications in human health, disease and therapy. In this talk, I will describe the development and application of an efficient and sensitive pipeline comprising experimental and analytic workflows for direct antigen identification and prediction from cell equivalents consistent with sample amounts harvested in clinical settings. Through detection and sequencing of thousands of peptides bound to distinct class I HLA-A and -B alleles using accurate mass, high-resolution liquid chromatography-mass spectrometry (LC-MS/MS), we are improving the understanding of the rules governing antigen processing and presentation. Currently, we are using this approach to identify peptides presented within multiple disease contexts such as cancer, inflammatory bowel disease, and infectious diseases.

Proteomics, Metabolomics and Lipidomics

9:30 a.m. – 12:15 p.m.

Understanding Molecular Mechanisms of Human Disease - A Critical Role for Proteomics and Metabolomics in Translational Research

The analytical power of the Orbitrap technology has been broadly leveraged in biomedical research and is now quickly being adopted in clinically-relevant problems to understand disease etiology. Translating basic scientific discoveries into an understanding of molecular mechanisms and the dynamics of signaling pathways requires sensitive, reproducible and robust quantitation of subtle changes in regulatory networks. In this session our speakers will explore multi-disciplinary and multi-omics approaches to quantify and untangle complex disease processes. They will present their latest breakthrough research in Proteomics, Glycomics, Metabolomics and Lipidomics.

Pharma and Biopharma

9:30 a.m. – 12:15 p.m.

Comprehensive Solutions for BioPharma Research and Development-Orbitrap Technology Powers Qualitative and Quantitative Applications from Complete Characterization to Lot Release

Orbitrap technology has become the preeminent mass analyzer for all aspects of BioPharma Discovery and Development. The unparalleled scan to scan mass accuracy, resolution, and precision combined with robustness and ease of use have resulted in its broad application across all stages of the BioPharma continuum. In this session, our speakers will demonstrate the application of this technology for the comprehensive characterization of complex biotherapeutics using Intact, Middle-Down, and Peptide Mapping approaches. High Resolution/Accurate Mass (HRAM) allows for unmatched selectivity and sensitivity for the quantitation of biotherapeutics even in the most complex matrices. In addition, it will be shown how the uncompromising performance of orbitrap technology drives a robust application that allows precise selective monitoring of multiple Critical Quality Attributes in a single validated method for lot release.

Environmental Analysis and Food Safety

9:30 a.m. – 12:15 p.m.

Advances in LC-MS Technologies for Safety and Efficacy of Food & Environmental Samples

Trace detection of known and unknown chemical contaminants, followed by targeted measurements of such are critical for safeguarding health and safety. The area of food integrity and authenticity is gaining importance as the science of proteomics and food safety merge. The analytical power of the Orbitrap technology, in combination with sub ppt level detection levels achieved by triple quadrupoles, allow total coverage of the workflows associated with such assays. In this meeting we will share the latest trends in these areas, with renowned guest speakers focusing on the analysis of pesticides, environmental contaminants and PDE5 inhibitors, as well as the latest software advancements in Unknown Screening and library search capabilities.

Clinical and Forensic

9:30 a.m. – 12:15 p.m.

Practical Application of Mass Spectrometry to Clinical Research, Forensic Toxicology, and Anti-Doping

Mass spectrometry is rapidly expanding into routine applications for biological examination. Accurate and individualized measurement of endogenous and exogenous compounds can influence the course of treatment and outcomes for everything from drug addiction to cancer. In this session, our expert speakers will share recent developments in protein marker discovery, development of lab developed tests (LDTs) for numerous diseases, and sensitive, accurate measurement of therapeutic and illicit drugs.

Booth 319

Hours

Sunday, June 57:45 p.m.9:30 p.m.
Monday, June 69:00 a.m.5:00 p.m.
Tuesday, June 79:00 a.m.5:00 p.m.
Wednesday, June 89:00 a.m.5:00 p.m.
Thursday, June 99:00 a.m.2:30 p.m.

Hospitality Suites

Connect with us in our two hospitality suites featuring MS technologies and software solutions.

Monday, June 6 – Wednesday, June 8

Grand Hyatt Hotel
600 E Market Street

Texas Ballroom D (MS Technologies)
Republic A, B, and C (Software Solutions)

Breakfast Workshops

Attend our Breakfast Workshops to learn how mass spectrometry innovations are beng translated into results from fellow scientists and Thermo Fisher Scientific experts.

Monday, June 6

Protein Structure: Cross-Linking / Top Down

Grand Hyatt

Texas Ballroom D

7:00 - 8:00 a.m.

Improved Workflows for Structural Proteomics: Studying Protein Interactions with MS-Cleavable Crosslinkers and Top/Middle Down HDX

In the last decade, chemical cross-linking combined with mass spectrometry (CX-MS) and hydrogen-deuterium exchange (HDX) have become increasingly powerful methods to probe the structure of protein complexes and interactions. The high resolution, mass accuracy Orbitrap technology in combination with enhanced fragmentation modes (e.g. HCD, ETD, EtHCD) and MSn modalities of the Orbitrap Fusion Lumos mass spectrometer makes it the ideal platform for structural proteomics studies. In addition to distinguished speakers presenting their latest work on protein structure elucidation, protein characterization and protein-protein interaction networks, the workshop will highlight new reagents, methods and software to make these cutting edge applications more accessible.

Charting the cellular interactome by proteome-wide cross-linking mass spectrometry
Fan Liu,
Postdoctoral Fellow,
Albert Heck Lab,
Utrecht University , Netherlands

Novel techniques and concepts in structural proteomics: crosslinking and top/middle down HDX combined with Orbitrap LC-MS/MS
Christoph Borchers,
Director,
UVic-Genome BC Proteomics Centre

HRAM Quan

Grand Hyatt

Republic ABC

7:00 - 8:00 a.m.

Unleashing the Power of HRAM for Quantitation

High Resolution Accurate Mass (HRAM) is implemented in all scan modes of the Thermo Scientific™ Q Exactive™ MS series of instruments. Each mode provides unique ways of leveraging the power of HRAM for quantitation. You will see how leading researchers in the field use these approaches for a broad range of applications. Full Scan HRAM supports Quan/Qual experiments and allows simultaneous targeted and non targeted quantitation. SIM and Multiplexed SIM provide high levels of selectivity without compromising ion intensity through fragmentation. PRM scan modes bring the power of HRAM selectivity to methods based on compound fragmentation. See how HRAM brings power, flexibility and unrivaled selectivity to quantitative experiments.

HRAM Quan using the LC Q Exactive Focus under the EU regulation for pesticide residues
Amadeo Fernando Albar,
Head of the EU Reference Lab for Food and Vegetables,
University of Almeria, Spain

High resolution accurate mass spectrometry for quantitative regulated bioanalysis: how, when, and why to implement
Robert M Sturm,
Assistant Research Investigator,
LCMS Biologics & Biomarkers

Tuesday, June 7

Digital Proteome Maps: Label-free Protein Quan/DIA

Grand Hyatt

Texas Ballroom D

7:00 - 8:00 a.m.

Improvements in Label-free Quantitation Methods for Reproducible Quantification of Proteins in Complex Mixtures

Recently, data independent acquisition (DIA) has emerged as a potential replacement technique to data dependent acquisition (DDA), the original data acquisition method driving most of proteomics today. DDA has been revered for its unparalleled ability to maximize peptide identification from complex mixtures, and remains the gold standard for label-free quantitation (LFQ) in proteomics to date. In this workshop we demonstrate how leading labs use DDA in combination with advanced software to address the issue of stochastic sampling to maximize reproducible protein quantitation that outperforms other LFQ methods. We will also demonstrate how advanced signal processing techniques optimize data mining of traditional shotgun proteomics experiments.

Unknown Unknowns - Structure ID

Grand Hyatt

Republic ABC

7:00 - 8:00 a.m.

Knowing the Unknown - Detection and Identification of Compounds of Interest in Complex Analysis

In many research applications, the ability to determine which components in a complex sample are of interest and then to identify them is a significant challenge. From emerging environmental contaminants, new endogenous metabolites in understudied species, food adulteration and authenticity, to a diverse range of other applications, this challenge requires tools to both determine the right peaks and identify them.

Smarter Tools for the Detection of Unknowns in Extremely Large Datasets
Ralf Tautenhahn
Thermo Fisher Scientific

mzCloud: Beyond the traditional library search
Robert Mistrik,
Chief Executive Officer,
HighChem Ltd

Wednesday, June 8

TMT

Grand Hyatt

Texas Ballroom D

7:00 - 8:00 a.m.

Advances in Accurate, High-Throughput Quantitative Proteomics

The ability to perform accurate protein quantification at low levels lets scientists unravel the complexity of protein interactions and track protein abundance changes in a wide variety of samples. When combined with multiplexing capabilities, quantitative proteomics provides a deep and comprehensive understanding of the molecular mechanisms underlying biological processes and disease states. Novel Thermo Scientific™ TMT10plex™ isobaric mass tag labeling combined with Orbitrap high resolution accurate mass (HRAM) mass spectrometry (MS) enable greater multiplexing capacity, resulting in increased depth of quantitative proteomic analysis across larger numbers of samples. The improved sensitivity and accuracy achieved with Orbitrap HRAM MS and synchronous precursor selection (SPS)-based MS3 technology on the Thermo Scientific™ Orbitrap Tribrid™ MS systems provide a unique, unmatched capability to accurately measure the most subtle changes in low-abundance proteins. In this workshop, we will discuss discovery and targeted approaches for multiplexed quantitative proteomics and present real-world applications from leading research laboratories.

High-Throughput multiplexed quantitative proteomics and phosphoproteomics to understand cancer drug resistance
Willi Haas,
Assistant Professor,
Harvard Medical School

Multiplexing targeted proteomics assays: Triggered by Offset Multiplexed High resolution Accurate mass Absolute Quantification (TOMAHAQ) on a Lumos Tribrid MS
Robert A Everley,
Research Associate in Systems Biology,
Harvard Medical School

Biopharma: Antibody Analysis

Grand Hyatt

Republic ABC

7:00 - 8:00 a.m.

Complete BioPharma Characterization from Compound Selection to Lot Release

Come meet our experienced team of biopharma scientists and learn how the power of the Orbitrap mass analyzer provides confident in-depth characterization of biotherapeutics at all stages of biopharma discovery, development and manufacture. See how superior Orbitrap mass resolution and accuracy supports the highly compressed gradients required for HDX analysis. Realize the power of Orbitrap technology for analyzing intact heterogeneous antibodies. Achieve unit mass resolution of mAb subunits for unequivocal mass assignments. Find clarity in top/middle sequencing with very high resolution and multiple fragmentation mechanisms. See the power of sophisticated algorithms paired with high-quality data-dependent MS/MS for peptide mapping and how HRAM analysis brings the future of biopharma lot release to today with the Multi Attribute Method (MAM).

Determination of higher order structure through the use of hydrogen deuterium exchange using Orbitrap technology
Terry Zhang,
Thermo Fisher Scientific

The power of the Orbitrap mass analyzer for online Intact analysis under native and denaturing conditions and subunt analysis.
Aaron O. Bailey,
Thermo Fisher Scientific

Characterization of mAbs through top/middle down and peptide mapping approaches
Stephane Houel,
Thermo Fisher Scientific

The Multi Attribute Method: HRAM peptide mapping for monitoriing critical quality attributes in lot release
Michael Blank,
Thermo Fisher Scientific

Thursday, June 9

Metabolomics/ Lipidomics (Targeted and Untargeted)

Henry B. Gonzalez Convention Center

Room 225CD

7:00 - 8:00 a.m.

High Confidence Targeted & Untargeted Metabolomics: Combining Comprehensive Chromatographic Separations, High Resolution Orbitrap Technology and Advanced Software

Join us for an engaging breakfast meeting to learn all about how the latest advancements in chromatography separation, Orbitrap technology and metabolomics software can help you identify and quantify more metabolites and lipid species with high confidence, thereby facilitating your targeted and untargeted metabolomics research.

Time resolved analysis of brain energy metabolism
by micro-dialysis linked ion chromatography-mass spectrometry
Yuki Sugiura,
Research Scientist,
Keio University School of Medicine, Japan

Comprehensive analysis of lipids by Integrating normal- and reversed-phase LC-MS
Qibin Zhang,
Associate Professor,
University of North Carolina at Greensboro

Booth 319

Hours

Sunday, June 57:45 p.m.9:30 p.m.
Monday, June 69:00 a.m.5:00 p.m.
Tuesday, June 79:00 a.m.5:00 p.m.
Wednesday, June 89:00 a.m.5:00 p.m.
Thursday, June 99:00 a.m.2:30 p.m.

Hospitality Suites

Connect with us in our two hospitality suites featuring MS technologies and software solutions.

Monday, June 6 – Wednesday, June 8

Grand Hyatt Hotel
600 E Market Street

Texas Ballroom D (MS Technologies)
Republic A, B, and C (Software Solutions)

Monday, June 6

Diagnostic Clinical Chemistry (Applications)
MP 090

Development of a High-throughput Hemoglobinopathies Workflow using High Resolution Accurate Mass Analysis

Drug and Metabolite Analysis: Novel Approaches for Dried Biological Samples
MP 101

Method Development Considerations for Paper-Spray Mass Spectrometry – Direct Ionization Technique for Physiological Fluid Analysis

Environmental Analysis: General (Part I)
MP 136

Method Optimization for Rapid Analysis of Brominated Flame Retardants in Polymers with DART-Orbitrap HRAM

Environmental Analysis: General (Part 1)
MP 142

Method Development for the Identification of Novel Brominated Flame Retardants using a Q Exactive HRAM Mass Spectrometer

Environmental Analysis: Pharmaceuticals and Pesticides
MP 164

An Unknown Screening Approach to Analyze Micropollutants Degradation by Different Disinfection Processes

High Mass Accuracy/High Performance MS Applications
MP 199

Orbitrap Fusion Tribrid Mass Spectrometer for Pharmaceutical Impurity Analysis

High Mass Accuracy/High Performance MS Applications
MP 207

Quantitative Evaluation of Immunosuppressant Drugs by High Resolution Accurate Mass using Full Scan and Selected Ion Monitoring Modes

Informatics: Metabolomics
MP 255

Building High Confidence Metabolite Libraries for Fast Identification in Targeted Profiling Experiments

Instrumentation: New Concepts
MP 298

Multiplexed Targeted Assays Using Ion Trap Waveform Isolation

Intact Proteins
MP 306

Development of a High-quality Intact Protein Standard for LC and MS Quality Control and Application Development

Intact Proteins
MP 308

The Use of Methionine Sulfoxide Reductases to Reverse Oxidized Methionine for Mass Spectrometry Applications

Intact Proteins
MP 312

Enabling Mass Spectrometric Analysis of Intact Proteins in Native Conditions on a Hybrid Quadrupole-Orbitrap Mass Spectrometer

LC-MS: Chromatography and Software (Part 1)
MP 412

Demonstration of Automated On-the-fly Retention Time Updating and SRM Method Visualization for Targeted Peptide Quantitation

LC-MS: Chromatography and Software (Part 1)
MP 415

High Resolution LC/MS Analysis of Therapeutic Oligonucleotides on a New Porous Polymer-based Reversed-phase Column

LC-MS: Chromatography and Software (Part 1)
MP 429

Increased MS Protein Identification Rates using 75 cm Long Nano LC C18 Separation Columns: Pushing the Limits of Bottom-Up Proteomics

Metabolomics: General
MP 490

Metabolomic Analysis of 13C/15N Labeled Metabolites Utilizing High Resolution Orbitrap Mass Spectrometry and Compound Discoverer Software

Metabolomics: General
MP 495

Wine Flavonoids Identified and Analyzed by Composite Neutral Loss Scan and Novel Data-dependent Scans for Metabolomics

Microorganisms: Identification and Characterization
MP 499

Detection of Penicillin Binding Protein 2a for the Identification of Methicillin Resistant S.aureus Using Top-down Proteomics

Proteomics: Quantitative
MP 649

Sensitive, Fast and Robust Quantification of Antibodies in Complex Matrices by Capillary Flow UHPLC and High Resolution Accurate Mass MS

Small Molecules: Qualitative Analysis
MP 661

The ETD-like Fragmentation for Small Molecules

Top Down Protein Analysis (Applications)
MP 710

Ultra-fast Analysis of Hemoglobin Isoforms using Capillary Electrophoresis Coupled to Mass Spectrometry and Ultraviolet Photodissociation

Tuesday, June 7

Antibodies & Antibody Drug Conjugates (Separations)
TP 022

Capillary Electrophoresis – Mass Spectrometry for Top Down Proteomics

Biomolecular Structure Analysis: Chemical Crosslinking and Covalent Labeling (Cross-Linking)
TP 061

Optimization of Crosslinked Peptide Analysis on an Orbitrap Fusion Lumos Mass Spectrometer

Data Independent Acquisition (SWATH)
TP 094

MS1 Based Quantification Optimization on DIA Methods on the Q Exactive HF Mass Spectrometer

Drug Discovery/DMPK/ADME (Applications)
TP 119

High Resolution Accurate Mass Quantitation of Iloperidone and Hydroxy Iloperidone Metabolites using Full Scan and Selected Ion Monitoring Modes

Drug Metabolism: Qualitative and High Throughput Analysis
TP 133

An Integrated Strategy for the Discovery and Identification of New Natural Product Metabolites by using Q-Orbitrap Mass Spectrometer and Multiple Data-Mining Approaches

FAIMS and DMS
TP 191

Modeling and Characterization of the Ion Transit Time in a FAIMS-MS Interface

FAIMS and DMS
TP 192

On a Multi-physics Computational Model to Understand Heat Exchange between FAIMS Electrode and Ion Transport Gas

FAIMS and DMS
TP 193

Efficiency of Ion Transmission between FAIMS Electrodes Without a Separation Electric Field

FAIMS and DMS
TP 195

Glyphosate Quantified in Black Tea by Automatically Optimized LC-FAIMS MS/MS

FAIMS and DMS
TP 201

Model FAIMS RF System using Neural Network

FAIMS and DMS
TP 202

Making FAIMS Faster, More Selective, and More Sensitive

Food Safety (Pesticides in Food)
TP 226

Routine Quantitative and Qualitative Methodologies for Food Pesticide Residue Laboratories using Tandem and High Resolution Accurate Mass (HRAM) LC/MS Instrumentation

Forensics (Part 1)
TP 254

Forensic Identification of Unknown Compounds in Human Urine using Complimentary Software with High-resolution Data and Theoretical Fragmentation Spectra

Informatics: Peptide ID and Quantification
TP 391

New Method for Label-free Quantification in the Proteome Discoverer Framework

Instrumentation: General
TP 393

Real-time Instrument Control of the Orbitrap Tribrid Mass Spectrometer

Instrumentation: New Developments in Mass Analyzers
TP 421

Design and Analytical Performance Evaluation of a Cooling Cell for a Quadrupole Mass Spectrometer with Enhanced Resolution and Sensitivity

Instrumentation: New Developments in Mass Analyzers
TP 427

Demonstration of using Isolation Waveform for Beam Type Selected-Reaction-Monitoring on a QqLIT Mass Spectrometer

Instrumentation: New Developments in Mass Analyzers
TP 442

Addressing the 100 Isotopologue Challenge: Orbitrap Mass Spectrometry as a Means of High-dimension Clumped and Position-specific Isotope Analysis

LC-MS: Chromatography and Software (Part 2)
TP 486

Exploring the Effects of Alternative Dynamic Exclusion Algorithms on Peptide Identification Experiments

LC-MS: Chromatography and Software (Part 2)
TP 489

UHPLC Optimization Study for Improved LC-MS Performance and Throughput

LC-MS: Chromatography and Software (Part 2)
TP 493

Long-term Test on a New Four-channel HPLC

Metabolomics: Untargeted Metabolite Profiling (Cells/Plants)
TP 554

Metabolomic Profiling of Food Diets using Ion Chromatography with High Resolution Orbitrap Mass Spectrometry

Phosphopeptides: Quantitative Analysis
TP 620

Evaluation of Search Engines for Phosphopeptide Identification and Quantitation

Phosphopeptides: Quantitative Analysis
TP 623

Sensitive and Accurate Quantitation of Phosphopeptides using TMT Isobaric Labeling

Proteomics: Clinical Applications (Development toward Clinical Application)
TP 670

Combined Analysis of Nucleic Acids and Protein for Cancer Research

Small Molecules: Quantitative Analysis (Animal, Plant/Insect, and Methodology)
TP 759

Parallel Reaction Monitoring and Selected Reaction Monitoring Exhibit Comparable Analytical Performance in Quantitative Analysis of Cannabinoid

Top Down Protein Analysis (Methodology)
TP 770

Development of Mass Spectrometry-based Methods for Quality Assessment of Recombinant Proteins

Wednesday, June 8

Antibodies & Antibody Drug Conjugates (Sequencing, Modifications & Hi Res)
WP 047

Middle-down Approach for Monitoring Monoclonal Antibody Variants and Deglycosylation

Antibodies & Antibody Drug Conjugates (Sequencing, Modifications & Hi Res)
WP 058

Top-down Characterization of Monoclonal Antibody on an Orbitrap Fusion Lumos Tribrid Mass Spectrometer

Antibodies & Antibody Drug Conjugates (Sequencing, Modifications & Hi Res)
WP 060

Full Characterization of Heterogeneous Antibody Samples Under Denaturing and Native/Native-Like Conditions on a Hybrid Quadrupole-Orbitrap Mass Spectrometer

Carbohydrates (Glycans)
WP 119

In-depth Analysis of Non-derivatized N-linked Glycans using Ion Chromatography-Orbitrap Mass Spectrometry

Drug Discovery/DMPK/ADME (General)
WP 162

Labeled Compound Detection using Compound Discoverer Pattern Scoring from High Resolution Mass Spectrometry

Environmental Analysis: Water Quality
WP 197

Cloud-based Analysis of Complex Sample Systems for Outlier and Trend Analysis in the Context of Water Monitoring

Environmental Analysis: Water Quality
WP 199

Unknown Profiling of Drinking Water using High Resolution LC-MS/MS and New Software

Environmental Analysis: Water Quality
WP 202

Quantitative Analysis of Nonylphenol Ethoxylates in Surface Water with UHPLC and HRAM Mass Spectrometry

Food Safety: Other Contaminants (Part 1)
WP 227

Ultra-fast Analysis of Allergens using Capillary Electrophoresis Coupled to Mass Spectrometry and Ultraviolet Photodissociation

Forensics (Part 2)
WP 263

Evaluation of Solid-phase Microextraction Sample Preparation for LC-MS Analysis of Drugs in Urine and Plasma for Forensics

Informatics: Algorithms and Statistical Advances
WP 388

Improving LC-MS Coverage through New Charge State and Monoisotopic m/z Assignment Algorithms

Informatics: Workflow and Data Management
WP 404

Xcalibur Workbench: A Lua Based Data Browser

Metabolomics: Untargeted Metabolite Profiling (Animal/Human/Other)
WP 559

Diabetes Markers: Using Orbitrap HRAM for Differential Analysis of Zucker Rat Plasma Metabolome

Thursday, June 9

Biomarkers: Discovery
(Part 2)
ThP 051

Facilitate Biomarker Discovery using Integrated “Omics” Differential Analysis with High Resolution Accurate LC/MS Approach

Biomarkers: Quantitative Analysis (Small Molecules & Metabolites)
ThP 089

Improvements in LFQ for Reproducible Quantification of Proteomic Experiments: How DDA Outperforms DIA

Food Safety: Other Contaminants (Part 2)
ThP 111

Determination and Quantification of Perchlorate in a Fruit Matrix using Accelerated Solvent Extraction and IC-MS

GCMS: Instrumentation and Applications (Applications)
ThP 149

Identification of Leachable Impurities from Pharmaceutical Container Closure Materials using Orbitrap-based GC-MS

GCMS: Instrumentation and Applications (Applications)
ThP 159

Chemical Profiling of Whiskies using Orbitrap GC-MS

H/D Exchange: Protein Structure/Function (Part 2)
ThP 180

Characterization of Conformation of Therapeutic Antibody Aggregation with Optimized Hydrogen/Deuterium Exchange Mass Spectrometry

Instrumentation: New Developments in Ionization and Sampling (Ionization)
ThP 303

Performance Evaluation of a Pneumatically Assisted Electrospray Ionization Source in the Microflow Regime

LC-MS: Sample Preparation (Part 2)
ThP 336

Rapid Online Desalting using a Supermacroporous Reversed Phase Cartridge for Mass Spectrometry Analysis of a Monoclonal Antibody

Peptides: Quantitative Analysis
ThP 474

Development of a MicroFlow LC-MS/MS Method for Quantitation of Peptides

Protein Therapeutics: Structural Characterization
ThP 546

Disulfide Bond Identification of Biotherapeutic Proteins using Various Fragmentation Techniques Available on an Orbitrap Fusion Tribrid Mass Spectrometer.

Protein Therapeutics: Structural Characterization
ThP 557

Complete Characterization of a Cysteine-linked Antibody-Drug Conjugate Performed on a Hybrid Quadrupole-Orbitrap Mass Spectrometer with High Mass Range

Proteins: PTMs (Part 2)
ThP 587

Comparison and Optimization of First and Second Generation Quadrupole Dual Cell Linear Ion Trap Orbitrap Hybrid MS for Glycopeptide Analysis

Proteomics: Quantitative (Pre-MS and Platforms-Informatics-MultiOmics-Dynamics)
ThP 635

Quantitative Analysis of AKT/mTOR Pathway using Multiplex-Immunoprecipitation and Targeted Mass Spectrometry

Small Molecules: Quantitative Analysis
(Part 2)
ThP 692

Evaluation of Two Sample Preparation Methods, Precipitation-Derivatization and SPE, for Quantitative LC-MS Analysis of Methylmalonic Acid in Plasma

Systems Biology (Protein Modifications and Cells)
ThP 711

Monitoring of the AKT/mTOR Pathway using Internal Standard Triggered-Parallel Reaction Monitoring (IS-PRM)

Toxicology
ThP 726

Increasing Sample Throughput for Detecting Drugs of Abuse and Metabolites in Urine by UHPLC-MS/MS for Forensic Toxicology

Booth 319

Hours

Sunday, June 57:45 p.m.9:30 p.m.
Monday, June 69:00 a.m.5:00 p.m.
Tuesday, June 79:00 a.m.5:00 p.m.
Wednesday, June 89:00 a.m.5:00 p.m.
Thursday, June 99:00 a.m.2:30 p.m.

Hospitality Suites

Connect with us in our two hospitality suites featuring MS technologies and software solutions.

Monday, June 6 – Wednesday, June 8

Grand Hyatt Hotel
600 E Market Street

Texas Ballroom D (MS Technologies)
Republic A, B, and C (Software Solutions)

Wednesday, June 8

MS in the QC Lab

Hemisfair 2

9:10 a.m.

Extending the Capabilities of a MS-based Multi-attribute Characterization Method to Promote Quality by Design in Biotherapeutic Drugs

Top Down Protein Analysis

Stars 4

3:10 p.m.

A Novel Approach to Sequencing Native Protein Complexes with an Orbitrap

Thursday, June 9

Informatics: Targeted Proteomics and DIA

Hemisfair 3

9:10 a.m.

Targeted Analysis of MS1 Data for Quantitative Studies

Fundamentals: Photodissociation

Room 221

10:10 a.m.

Performance Considerations for Ultraviolet Photo-dissociation using the Nd:YAG 5th Harmonic (213nm)

Booth 319

Hours

Sunday, June 57:45 p.m.9:30 p.m.
Monday, June 69:00 a.m.5:00 p.m.
Tuesday, June 79:00 a.m.5:00 p.m.
Wednesday, June 89:00 a.m.5:00 p.m.
Thursday, June 99:00 a.m.2:30 p.m.

Hospitality Suites

Connect with us in our two hospitality suites featuring MS technologies and software solutions.

Monday, June 6 – Wednesday, June 8

Grand Hyatt Hotel
600 E Market Street

Texas Ballroom D (MS Technologies)
Republic A, B, and C (Software Solutions)

Thermo Scientific Annual Customer Appreciation Event

Thermo Fisher Scientific

Historic Sunset Station is located just one hundred yards north of the Alamodome and a short walk from the Henry B. Gonzalez Convention Center. For those requiring assistance, limited transportation will be available between the convention center and Sunset Station throughout the duration of the event. Sunset Station is an indoor/outdoor venue. Please dress comfortably.

Join us and see San Antonio’s rich culture come alive through history, art, architecture, food, and live music!

When:

June 5, 2016
12:30 – 3:00 p.m.

Where:

Historic Sunset Station
1174 E Commerce St, San Antonio, TX 78205

Get directions

Booth 319

Hours

Sunday, June 57:45 p.m.9:30 p.m.
Monday, June 69:00 a.m.5:00 p.m.
Tuesday, June 79:00 a.m.5:00 p.m.
Wednesday, June 89:00 a.m.5:00 p.m.
Thursday, June 99:00 a.m.2:30 p.m.

Hospitality Suites

Connect with us in our two hospitality suites featuring MS technologies and software solutions.

Monday, June 6 – Wednesday, June 8

Grand Hyatt Hotel
600 E Market Street

Texas Ballroom D (MS Technologies)
Republic A, B, and C (Software Solutions)

ASMS 2016

June 5 - June 9, 2016

Visit ASMS website

ASMS 2016 - Thermo Fisher Scientific