Active Ion Management Delivers
Attogram Sensitivity on TSQ Quantiva
The Thermo Scientific™ TSQ Quantiva™ triple-stage quadrupole mass spectrometer has all of the speed, dynamic range and robustness you need for the most difficult quantitative challenges. Extreme quantitiative performance is powered by Thermo Scientific™ active ion management (AIM™) technology, giving you maximum signal, lowest noise and preventing contamination.
Download Brochure ( 6MB )New Software Maximizes Usability
Tune
Method Editor
Drag-and-Drop Method Development
The new, intuitive method editor allows you to rapidly build a
method by dragging and dropping components into place for complex
SRM experiments. Tune and calibration functionality has been
radically redesigned, greatly reducing keystroking and set-up time.
FreeStyle
Powerful and Flexible Data Visualization
Thermo Scientific™ FreeStyle™ software is designed to give you
maximum information from SRM and other quantitative experiments. An
intuitive, easy to use interface places many functions just one
mouse click away. Manage and view complex sequence files with ease.
Analysis
Transform your Science
With unprecedented experimental power,unrivaled sensitivity and usability of the Orbitrap Fusion MS and TSQ Quantiva MS, unlock new powerful workflows for comprehensive discovery, structural elucidation and quantitation of complex samples to obtain results never before achievable.
Poster Notes
Proteomics
This next generation of Thermo Scientific mass spectrometers is poised to transform proteomics and biological research, allowing you to investigate biological systems in new ways and acquire better, faster answers to fundamental questions.
The Thermo Scientific™ Orbitrap Fusion™ Tribrid™ mass spectrometer combines the best of quadrupole, Orbitrap, and ion trap mass analysis; multiple fragmentation modes; and outstanding mass resolution to help researchers dig deeper into the proteome; identify more, lower-abundance proteins more quickly; make quantitative comparisons over more experimental conditions; and elucidate structures more comprehensively. For biomarker candidate validation and other high-volume targeted protein quantitation applications, the Thermo Scientific™ TSQ Quantiva™ triple quadrupole MS provides the extreme sensitivity and speed needed to detect and quantify biologically significant low-abundance proteins in complex biological matrices.
Metabolomics and Lipidomics
Metabolomics has the potential to revolutionize biological research and personalized medicine. New discoveries will arise from the detection, rapid identification, and validation of key metabolites and their pathways as physiological markers of biological systems. The next generation of Thermo Scientific mass spectrometers is poised to transform metabolomics.
The Thermo Scientific™ Orbitrap Fusion™ Tribrid™ mass spectrometer enables metabolite profiling with simultaneous in-depth structural elucidation-at UHPLC speed-overcoming one of the major bottlenecks in discovery metabolomics.
For targeted metabolite quantitation, the Thermo Scientific™ TSQ Quantiva™ triple quadrupole MS provides the extreme sensitivity and speed needed today,allowing you to focus on the most demanding aspects of routine compound quantitation - detection of low level metabolites in complex biological matrices and faster biomarker candidate validation.
Poster Notes
Biopharmaceutical
From assessing biological properties, heterogeneity, degradation, and metabolic pathways, to quantitative bioanalysis, researchers need fast, high-quality data to inform biopharmaceutical development decisions. Thermo Scientific™ Orbitrap™ technology offers an unequalled combination of high resolution and accurate mass (HR/AM), sensitivity, and dynamic range to address these needs.
The Thermo Scientific™ Q Exactive™ MS enables fast confirmation of mass and primary sequence, heterogeneity, and purity, allowing quicker, more confident decisions about how to proceed with biotherapeutic development.The new Thermo Scientific™ Orbitrap Fusion™ MS with a unique Tribrid architecture provides more detailed structural elucidation, both at the peptide level and top-down sequencing of intact proteins. Precise location and identification of post-translational modifications means more complete characterization of biologics and biosimilars.
For targeted quantitation, the Thermo Scientific™ TSQ Quantiva™ triple quadrupole MS provides extreme attomole sensitivity and speed to meet the most demanding aspects of quantitation: detection of low-level compounds in complex biological matrices and high-throughput protein-drug pharmacokinetic studies. Regulatory compliance is available with the proven Thermo Scientific™ LCQuan™ and Watson LIMS™ software, and usability is built in with supporting method development workflows for targeted biotherapeutic analysis.
Pharmaceutical
The identification of the structure of small molecules is a diverse area with applications in pharmaceutical metabolite identification, extractables and leachables, impurities, and degradation analysis. For each of these applications, the ability to confidently detect and identify small molecule species provides critical decision making information to meet regulatory requirements as well as improve product safety and quality.
The Thermo Scientific™ Orbitrap Fusion™ Tribrid™ mass spectrometer uses the power of three mass analyzers and multiple fragmentation modes to deliver fast, unambiguous structural elucidation and more definitive identification of small molecules.
For targeted quantitation in bioanalysis or process monitoring, the Thermo Scientific™ TSQ Quantiva™ triple quadrupole MS provides the extreme sub-attomole sensitivity and speed needed for quantitation of low level compounds in complex matrices. Regulatory compliance is available with the proven Thermo Scientific™ LCQuan™ and Watson LIMS™ software, and usability is built in with supporting method development workflows for targeted bioanalysis.
Clinical Research and Forensic Toxicology
Clinical research and forensic toxicology fight a constant battle to detect and quantify ever-lower amounts of compounds in complex matrices-with greater accuracy and in less time. To meet these challenges, Thermo Fisher Scientific has developed two new triple-stage quadrupole mass spectrometers that deliver extreme performance and value with unprecedented robustness and ease of use.
For ultimate quantitative performance, the Thermo Scientific™ TSQ Quantiva™ MS powered by active ion management (AIM™) technology provides attogram sensitivity with outstanding robustness and ease of use. The Thermo Scientific™ TSQ Endura™ MS offers the ultimate in quantitative value, with LODs and LOQs unrivaled in its class. It does so with a simplicity that takes the worry out of method development and operation. Pair these with a Thermo Scientific™ Prelude SPLC™ system to increase productivity through analysis multiplexing and reduced sample preparation. Thermo Scientific™ Tracefinder™ software with supporting methods and easy to use instrument control further maximizes sample throughput.
Poster Notes
Environmental and Food SafetyTesting
Environmental and food safety fight a constant battle to detect and quantify ever-lower amounts of compounds-often in challenging matricies-with greater accuracy and in less time. To meet these challenges, Thermo Fisher Scientific has developed two new triple-stage quadrupole mass spectrometers that deliver extreme performance and value with unprecedented robustness and ease of use.
For ultimate quantitative performance, the Thermo Scientific™ TSQ Quantiva™ MS powered by Thermo Scientific™ active ion management (AIM™) technology provides attogram sensitivity with outstanding robustness and ease of use. The Thermo Scientific™ TSQ Endura™ MS offers the ultimate in quantitative value, with LODs and LOQs unrivaled in its class. It does so with a simplicity that takes the worry out of method development and operation.
Either system can be paired with a Thermo Scientific™ Prelude SPLC™ system or Transcend™ system to increase productivity through analysis multiplexing and reduced sample preparation. Thermo Scientific™ Tracefinder™ software with supporting methods and easy to use instrument control further maximizes sample throughput.
TSQ Endura MS
Extreme Quantitative Value
The Thermo Scientific™ TSQ Endura™ triple-stage quadrupole mass spectrometer provides unparalleled value, with LODs and LOQs unrivaled in its class. It delivers this best-in-class quantitation run-after-run and day-after-day regardless of sample type or matrix, and it does so with a simplicity that takes the worry out of method development and operation.
