Find the Best LC Solution for Your LC/MS Applications
Liquid chromatography/mass spectrometry (LC/MS) provides the analytical power needed to detect, identify , characterize, and quantify the widest possible range of compounds in simple or complex matrices. The Thermo Scientific brand offers a unique combination of best-in-class LC technology, industry-leading mass spectrometry systems, and powerful data analysis tools that address a full range of qualitative and quantitative applications.
Proteomics Metabolomics and Lipidomics Biopharmaceutical
Pharmaceutical Clinical Research and Forensic Toxicology Environmental and Food Safety Testing
Discovery Proteomics
The Thermo Scientific™ Easy-nLC 1000 and Thermo Scientific™ Dionex™ UltiMate™ 3000 RSLCnano systems are an integrated part of your LC/MS discovery proteomics workflows delivering unparallelled separation efficiency and speed. Together with the Thermo Scientific™ Orbitrap Fusion™ Tribrid™ MS also designed for highest sensitivity, and speed, we enable the generation of hundreds of thousands of relevant protein quantification measurements and new workflows – to offer a novel tool for cell biology and molecular medicine that will become quickly indispensible in leading research laboratories.
Targeted Proteomics
The Easy-nLC 1000 and Thermo Scientific™ Dionex™ UltiMate™ 3000 RSLCnano systems are an integrated part of your LC/MS targeted proteomics workflows delivering unparallelled separation efficiency, reproducibility and speed. Together with the Thermo Scientific™ TSQ Quantiva™ MS and its ulitmate sensitivity,speed, and reproducibility, you can focus on the most demanding aspects of routine protein quantitation- detection of low level peptides in complex biological matrices in hundreds or thousands of biological samples
Discovery Metabolomics
The Thermo Scientific™ Dionex™ UltiMate™ 3000 Rapid Separation LC (RSLC) systems integrate unique hardware features for ultrafast separations and excellent resolution on columns with small particles. Together with the Thermo Scientific™ Orbitrap Fusion™ Tribrid™ MS, designed for highest sensitivity, speed, and flexible MSn workflows, for the first time, metabolite profiling with simultaneous structural elucidation for compound identification at UHPLC speed is now truly possible. This enables new discoveries will arise from the detection and rapid identification of key metabolites and their pathways as physiological markers of the biological system.
Targeted Metabolomics
The Thermo Scientific™ Dionex™ UltiMate™ 3000 Rapid Separation LC (RSLC) systems integrate unique hardware features for ultrafast separations and excellent resolution on columns with small particles. Together with the Thermo Scientific™ TSQ Quantiva™ MS and its ulitmate sensitivity,speed, and reproducibility, you can focus on the most demanding aspects of routine compound identification- detection of low level metabolites in complex biological matrices in hundreds or thousands of biological samples
Mass Spectrometer:
Orbitrap Fusion MSLC System:
UltiMate 3000 BioRS LC SystemEasy nLC-1000 LC System
Biologics Characterization
The Thermo Scientific™ Dionex™ UltiMate™ 3000 BioRS system was developed for reliability and robust biomolecule analysis, providing UHPLC capabilities for all stages in biopharmaceutical analysis with column switching capabilties that enable MS integration. The Thermo Scientific™ Easy-nLC 1000 system delivers unparallelled separation efficiency, reproducibility and speed. Together with the Thermo Scientific™ Orbitrap Fusion™ Tribrid™ MS - these LC/MS systems exceed the demands of comprehensive biomolecule characterization from biotherapeutic drug development through manufacturing. The unique Tribrid architecture enables faster peptide mapping, impurity and sequence variant characterization and improved identification of low level drug metabolites in complex matrices.
Pharmaceutical Structural Elucidation
The Thermo Scientific™ Dionex™ UltiMate™ 3000 Rapid Separation LC (RSLC) systems integrate unique hardware features for ultrafast separations and excellent resolution on columns with small particles. Together with the Thermo Scientific™ Orbitrap Fusion™ Tribrid™ MS designed for highest sensitivity, speed, and flexible MSn workflows, we deliver fast, unambiguous structural elucidation and more definitive identification of small molecules at UHPLC speed - enabling confident detection and identification of small molecule species to provide critical decision making information to meet regulatory requirements as well as improve product safety and quality.
Pharmaceutical Bioanalysis
The Thermo Scientific™ Dionex™ UltiMate™ 3000 Rapid Separation LC (RSLC) systems integrate unique hardware features for ultrafast separations and excellent resolution on columns with small particles. Together with the Thermo Scientific™ TSQ Quantiva™ MS and its ulitmate sub-attomole sensitivity,speed, and reproducibility, you can focus on your most demanding bioanalytical applications. Regulatory compliance is available with the proven Thermo Scientific™ LCQuan™ and Watson LIMS™ software, and usability is built in with supporting method development workflows for targeted bioanalysis.
Clinical Research/ Forensic Toxicology
The Thermo Scientific™ Prelude SPLC™ system incorporates two channels of high-performance liquid chromatography (HPLC) separation with automated sample cleanup to enhance LC-MS/MS sensitivity.For ultimate productivity, the Thermo Scientific™ Transcend™ system with four channels of multiplexing further increase the efficiency of your mass spectrometry workflow. Together with the Thermo Scientific™ TSQ Quantiva™ and TSQ Endura™ triple quadrupole MS with the highest sensitivity, robustness and usability today , these LC/MS systems allows you to focus on the most demanding aspects of clinical and forensics research by delivering the highest productivity day in day out. You can now accurately detect and quantify very low level amounts of compounds in complex biological samples such as blood, urine and oral fluid.
Mass Spectrometer:
TSQ Quantiva MSTSQ Endura MS
LC System:
Ultimate 3000 RSLC Binary LC SystemEquan Max Plus System
Environmental Testing
The Thermo Scientific™ Dionex™ UltiMate™ 3000 Rapid Separation LC (RSLC) systems integrate unique hardware features for ultrafast separations and excellent resolution on columns with small particles. For ultimate productivity, the Thermo Scientific™ EQUAN Max Plus™ system provides a turn-key automated solution which includes online sample preparation and a range of LC separations.Together with the Thermo Scientific™ TSQ Quantiva and TSQ Endura™ triple quadrupole MS with the highest sensitivity, robustness and usability today , these LC/MS systems allows you to focus on the most demanding aspects of environmental testing, throughput , reliability and performance to meet and exceed needs today and in the future with changing regulatory demands.
Mass Spectrometer:
TSQ Quantiva MSTSQ Endura MS
LC System:
Ultimate 3000 RSLC Binary LC SystemTranscend System
Food Safety Testing
The Thermo Scientific™ Dionex™ UltiMate™ 3000 Rapid Separation LC (RSLC) systems integrate unique hardware features for ultrafast separations and excellent resolution on columns with small particles. For ultimate productivity, the Transcend system combines the power of automated online sample preparation and multiplexing to increase the efficiency of your mass spectrometry workflow.Together with the TSQ Quantiva™ and TSQ Endura™ MS with the highest sensitivity, robustness and usability today , these LC/MS systems allows you to focus on the most demanding aspects of food safety testing, throughput , reliability and performance to meet and exceed needs today and in the future with changing regulatory demands.
