Annual Users' Meeting

We invite you for a morning of learning about the latest in -omics, bioanalysis, environmental, food safety, clinical research and forensic toxicology. See how innovative Thermo Scientific™ technology is used by industry leaders to solve some of today's toughest analytical challenges.

Plenary Speakers

Join us in welcoming our plenary speaker, Alexander Makarov, Ph.D., distinguished physicist and lead scientist of Thermo Scientific™ Orbitrap™ technology and Nevan Krogan, Ph.D., Professor at University of California-San Francisco and Associate Investigator at the J. David Gladstone Institutes.

Alexander Makarov, Ph.D.

Nevan Krogan, Ph.D.

Alexander Makarov, Ph.D

In 1996, Alexander joined HD Technologies, a small high-tech company that was formed by Steve Davis and Andy Hofmann and located in Manchester, UK. Although the company specialized in contract development of TOFMS systems, Alexander started to deviate from this technology and made his first steps towards the concept of the Orbitrap mass analyzer. Alexander's proof-of-principle results were presented at the ASMS Conference and the term "Orbitrap analyzer" was used for the first time in 1999.

Nevan Krogan, Ph.D.

Dr. Krogan is a leader in the field of systems biology. His lab develops and utilizes tools for the systematic interrogation of various biological systems, including model organisms like budding yeast and E. coli, as well as mouse and human cells. His group primarily focuses on generating and analyzing protein-protein and genetic interaction data as well as post-translationational modifications. More recently, the group has been using these systems methodologies to study host-pathogen relationships.

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Plenary Session

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8 - 8:15 a.m.	Introduction Ken Miller, Life Sciences Mass Spectrometry, Thermo Fisher Scientific
8:15 - 8:50 a.m.	Transforming Your Science: Fundamental Advances in LC/MS Alexander Makarov, Ph.D., Thermo Fisher Scientific
8:50 - 9:25 a.m.	From Systems to Mechanism: Deriving Functional Insights From Proteomic Approaches Nevan Krogan, Ph.D., Cellular & Molecular Pharmacology, UCSF School of Medicine

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Proteomics, Metabolomics & Lipidomics Track

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9:40 - 9:55 a.m.	Introduction Julian Saba, Ph.D., Thermo Fisher Scientific
9:55 - 10:20 a.m.	From Noise to Signal: Proteome-Wide Multiplexed Quantitation using the MultiNotch MS3 Method Attains a New Level of Sensitivity, Precision and Accuracy Graeme McAlister, Ph.D., Dept. Cell Biology, Harvard Medical School
10:20 - 10:45 a.m.	Intervention: Overcoming your Dependence on Data Dependant Acquisition Michael MacCoss, Ph.D., University of Washington School of Medicine
10:45 - 11:10 a.m.	Structure Activity Relationships of Nuclear Receptor, GPCR and Kinase Modulators Revealed with Differential HDX Patrick R. Griffin, Ph.D., Dept. Molecular Therapeutics, The Scripps Research Institute
11:10 - 11:25 a.m.	Coffee Break
11:25 - 11:50 a.m.	Metabolic Profiling of Human Disease and Model Systems Clary Clish, Ph.D., Broad Institute of MIT and Harvard
11:50 a.m. - 12:15 p.m.	Comprehensive Lipidome Profiling by Ultrahigh Resolution ESI-MS and MS/MS to Identify Biomarkers of Diabetic Retinopathy Gavin E. Reid, Ph.D., Biochemistry and Molecular Biology, Michigan State University

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Pharma & Biopharmaceuticals Track

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9:40 - 9:55 a.m.	Introduction Patrick Bennett, Thermo Fisher Scientific
9:55 - 10:20 a.m.	HRMS Bioanalysis of Micro Samples Employing Membrane-Based Dried Matrix Spots: An Alternative to Cellulose DBS Substrates Rob Sturm, Ph.D., Quintiles
10:20 - 10:45 a.m.	Creation of Rich MSn Data for Structure Elucidation in Quan/Qual Analysis: Applications of Combined HCD/CID and New Isolation Techniques Jonathan Josephs, Ph.D, Principal Scientist, Bristol-Myers Squibb
10:45 - 11:10 a.m.	The Main Cause of Amino Acid Misincorporations in Recombinant Proteins Zhongqi Zhang, Scientific Director, Amgen
11:10 - 11:25 a.m.	Coffee Break
11:25 - 11:50 a.m.	Exploring Latest Innovations in Orbitrap Technology for In-Depth Characterization of Recombinant Proteins Melissa Alvarez, Senior Research Associate, Genentech
11:50 a.m. - 12:15 p.m.	Leveraging the Intrinsic Properties of CESI-MS (Capillary Electrophoresis-Electrospray Ionization- MS) for Achieving Highly Informative Peptide Mapping of Monoclonal Antibodies Jean-Marc Busnel, Ph.D., Beckman Coulter

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Environmental Analysis, Food Safety & Clinical Research Track

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9:40 - 9:55 a.m.	Introduction Dipankar Ghosh, Ph.D., Thermo Fisher Scientific
9:55 - 10:20 a.m.	Implementation of the Prelude SPLC System in the Clinical Research Laboratory: A Users Perspective Roy Peake, Ph.D., Dept. Clinical Chemistry, Boston Children’s Hospital
10:20 - 10:45 a.m.	Paperspray – A Revolution in High Throughput Blood Spot Analysis Nick Manicke, Ph.D, Chemistry Department, Purdue University
10:45 - 11:10 a.m.	Advances in Triple Quad MS Technology and the Impact on Clinical Research Marta Kozak, Thermo Fisher Scientific
11:10 - 11:25 a.m.	Coffee Break
11:25 - 11:50 a.m.	Multi Antibiotic Residue Detection - Status Quo and Challenges for Confirmatory and Screening Approaches Scarlett Biselli, Ph.D., Eurofins, Hamburg
11:50 a.m. - 12:15 p.m.	LC-Orbitrap Based Qualitative, Quantitative, and Standard-less Analysis of Environmental Pollutants of Emerging Concern Paul Yang, Ph.D., Ontario Ministry of the Environment, Canada

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